The first anti hair loss and growth product that people with hair loss problems come into contact with is probably Minoxidil.
Minoxidil is the most widely used drug, with a mature promotional model and already deeply ingrained in people’s hearts. In this article, we have compiled comprehensive Minoxidil information.
Research purpose of Minoxidil : treat hypertension
Although 2% and 5% Minoxidil now is best known for hair loss and hair regrowth.But do you know Minoxidil was originally used to treat severe and refractory hypertension.
It seems that hypertension and hair loss are two completely different treatment directions, but Minoxidil’s mode of action combines these two conditions, which we will explain in detail later. Minoxidil was initially developed for the treatment of hypertension, but during its use in hypertensive patients, doctors found that balding patients experienced hair regeneration and systemic hirsutism (as it was taken orally). Subsequently, it began to be used for the treatment of male androgenic alopecia (AGA), and then for the treatment of female alopecia.
How Minoxidil works in treating hair loss?
Minoxidil is the most widely used drug for treating hair loss, but its exact mechanism of action is still not fully understood. But our performance in various experiments can be glimpsed.

1. Open potassium ion channels to assist in the proliferation and development of new hair follicle cells.
Minoxidil is an effective small artery vasodilator that can open potassium channels located on the smooth muscle of peripheral arteries, leading to cell membrane hyperpolarization. Potassium ion channel activity plays a crucial role in early cell proliferation. In practical use, it has also been found that Minoxidil increases cell DNA synthesis and enhances cell proliferation. This helps to facilitate the proliferation and development of new hair follicle cells.
The vasodilation effect of Minoxidil can improve blood circulation in the scalp area, bringing more nutrients and oxygen to the scalp area, which is beneficial for the health of hair follicles and hair.
2.Minoxidil induces β- The activity of sericin stimulates hair follicle proliferation and differentiation, prolonging the growth period of dermal papilla (DP).
After normal hair loss, there will be a rest period, after which hair will grow. The hair that grows will go through a growth period, and after reaching a certain length, it will enter the shedding period again, in this cycle. Research has shown that using Minoxidil simultaneously prolongs the growth period of hair and shortens the resting period of hair, thereby extending the interval between two growth periods of human hair.
The process of Minoxidil is induced by β- It is achieved through the activity of sericin. During this process, Minoxidil also increases the size of hair follicles and the percentage of follicles in the early stages of hair growth, leading to the growth of m...

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